Creamy Pesto Penne Chicken

Featured in: Cozy Weeknight Dinners

This Italian-inspired dish combines tender chicken pieces with perfectly cooked penne pasta, all tossed in a silky creamy pesto sauce. The sauce blends basil pesto, cream, and Parmesan, creating a luscious coating that complements the savory chicken. Aromatic garlic and onions add depth, while fresh basil and extra Parmesan garnish elevate the flavors. Quick to prepare, it’s ideal for weeknight meals or casual gatherings, delivering comfort and rich taste in every bite.

Updated on Sat, 15 Nov 2025 08:44:00 GMT
Golden-brown chicken and penne pasta swimming in creamy pesto sauce, a satisfying meal. Save
Golden-brown chicken and penne pasta swimming in creamy pesto sauce, a satisfying meal. | toastytongs.com

A comforting Italian-inspired pasta dish featuring tender chicken, al dente penne, and a luscious creamy pesto sauce. Perfect for weeknight dinners or casual gatherings.

I first discovered how much my family loves creamy pesto pasta during a busy week when I needed something fast that still tasted homemade. Watching everyone gather around the table and reach for seconds was the best reward.

Ingredients

  • Boneless Skinless Chicken Breasts: 2 (about 400 g), cut into bite-sized pieces
  • Penne Pasta: 350 g
  • Heavy Cream: 200 ml
  • Grated Parmesan Cheese: 40 g
  • Basil Pesto: 80 g (store-bought or homemade)
  • Onion: 1 small, finely chopped
  • Garlic: 2 cloves, minced
  • Olive Oil: 2 tbsp
  • Salt and Freshly Ground Black Pepper: to taste
  • Fresh Basil Leaves (optional): to garnish
  • Extra Grated Parmesan (optional): to garnish

Instructions

Cook Pasta:
Cook the penne pasta in a large pot of salted boiling water until al dente, according to package instructions. Drain, reserving 100 ml of pasta water.
Cook Chicken:
While the pasta cooks, heat olive oil in a large skillet over medium-high heat. Add the chicken pieces, season with salt and pepper, and saute for 5–6 minutes until golden brown and cooked through. Remove and set aside.
Saute Onion & Garlic:
In the same skillet, add the chopped onion and cook for 2–3 minutes until softened. Add minced garlic and saute for 30 seconds until fragrant.
Make Sauce:
Reduce heat to medium. Pour in the heavy cream and bring to a gentle simmer. Stir in the pesto and Parmesan cheese, mixing until smooth.
Combine Chicken & Sauce:
Return the cooked chicken to the skillet and toss to coat in the sauce.
Toss Pasta:
Add the drained penne to the skillet, tossing to combine. Add reserved pasta water as needed to achieve desired sauce consistency.
Season & Serve:
Season with additional salt and pepper to taste. Serve immediately, garnished with fresh basil and extra Parmesan if desired.
A flavorful plate piled high with Creamy Pesto Penne & Chicken, ready for enjoying. Save
A flavorful plate piled high with Creamy Pesto Penne & Chicken, ready for enjoying. | toastytongs.com

Making this meal became an instant family tradition for us. Every time I serve it, my kids claim the leftovers for their lunchboxes before we even finish dinner.

Serving Suggestions

Pair with a crisp green salad and garlic bread for a complete meal. For drinks, try sparkling water with lemon or a chilled glass of Pinot Grigio.

How to Store

Leftovers keep in an airtight container in the refrigerator for up to 3 days. Reheat gently in a skillet with a splash of cream or milk to loosen the sauce.

Ingredient Swaps

Swap chicken for shrimp, or use sun-dried tomato pesto for a flavorful twist. Whole wheat pasta or gluten-free options can also be used if needed.

Savory Creamy Pesto Penne & Chicken, perfectly cooked and topped with fresh basil leaves. Save
Savory Creamy Pesto Penne & Chicken, perfectly cooked and topped with fresh basil leaves. | toastytongs.com

This creamy pesto penne with chicken is sure to become a regular in your meal rotation. Enjoy every comforting, flavorful bite!

Recipe FAQ

How can I ensure the penne is cooked al dente?

Cook the penne in boiling salted water according to package instructions, typically 10-12 minutes, then test for a slight firmness to the bite before draining.

Can I use homemade pesto instead of store-bought?

Absolutely. Homemade basil pesto adds a fresh and vibrant flavor that pairs wonderfully with the creamy sauce.

What is the best way to prevent the cream sauce from curdling?

Simmer the cream gently over medium heat without boiling, and stir constantly when adding pesto and Parmesan to maintain a smooth sauce.

How do I keep the chicken tender during cooking?

Sauté chicken pieces over medium-high heat until golden and cooked through, about 5–6 minutes, avoiding overcooking which can dry them out.

Can I substitute heavy cream with a lighter option?

Yes, half-and-half or whole milk can be used for a lighter sauce, though it will be less rich and slightly thinner in texture.

Creamy Pesto Penne Chicken

Tender chicken and al dente penne in a rich, creamy pesto sauce with Parmesan and fresh basil.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min
Created By Daniel Brooks


Skill Level Easy

Heritage Italian

Output 4 Portions

Dietary considerations None specified

Components

Poultry

01 2 boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 12.3 oz penne pasta

Dairy

01 3/4 cup heavy cream
02 1/3 cup grated Parmesan cheese

Pesto

01 1/3 cup basil pesto

Vegetables

01 1 small onion, finely chopped
02 2 cloves garlic, minced

Pantry

01 2 tablespoons olive oil
02 Salt and freshly ground black pepper, to taste

Garnish (optional)

01 Fresh basil leaves
02 Extra grated Parmesan cheese

Directions

Phase 01

Cook pasta: Bring a large pot of salted water to a boil and cook the penne according to package instructions until al dente. Drain, reserving 1/3 cup of pasta water.

Phase 02

Sauté chicken: Heat olive oil in a large skillet over medium-high heat. Season chicken pieces with salt and pepper, then sauté for 5 to 6 minutes until golden brown and fully cooked. Remove from skillet and set aside.

Phase 03

Cook aromatics: In the same skillet, add chopped onion and cook for 2 to 3 minutes until softened, then add minced garlic and sauté for 30 seconds until fragrant.

Phase 04

Prepare sauce: Reduce heat to medium and pour in heavy cream. Bring to a gentle simmer, then stir in basil pesto and grated Parmesan until the sauce is smooth.

Phase 05

Combine chicken and sauce: Return the cooked chicken to the skillet and toss to coat evenly with the sauce.

Phase 06

Finish the dish: Add the drained penne to the skillet and gently toss to combine. Add reserved pasta water as needed to achieve a creamy consistency. Adjust seasoning with salt and pepper.

Phase 07

Serve: Serve immediately, garnished with fresh basil leaves and additional grated Parmesan if desired.

Tools needed

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Colander

Allergy details

Review each ingredient for potential allergens and consult with a healthcare professional if you're uncertain.
  • Contains dairy (cream, Parmesan), wheat (pasta), and possibly nuts (pine nuts in pesto).
  • Check pesto ingredients carefully for allergens.

Nutritional information (per portion)

These values are approximate guidelines only and shouldn't replace professional medical guidance.
  • Energy: 620
  • Fats: 27 g
  • Carbohydrates: 58 g
  • Proteins: 36 g